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GABA vs Ashwagandha (Can You Take Them Together?)

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So you’ve decided to take some supplements to improve your wellbeing.

If you’re here, I’m guessing you’re most interested in supps that are:

  • Safe
  • Effective
  • Not too pricey

Am I correct?

If that sounds like you, I’ve got fantastic news. There are a ton of great supplements that will fit the bill.

Two good options that you may be aware of are GABA and Ashwagandha. I’m here to help you figure out which one is right for you.

In my ever-growing Supplement Comparison Series, I take 2 supplements and compare them on their price, benefits, side effects and more. Hopefully, by the end of this article, you’ll have a better idea of which one to take.

In this post, we’ll take a look at GABA vs Ashwagandha.

Is GABA Better Than Ashwagandha?

You should take GABA if you want to reduce stress, reduce high blood pressure or improve your sleep. Whereas you should take Ashwagandha if you want to increase testosterone levels, gain more muscle or reduce high blood sugar levels.

What is GABA?


GABA (Gamma-Aminobutryic acid) is an amino acid that’s naturally produced in the brain.

It works as a neurotransmitter, meaning it facilitates communication among brain cells.

GABA’s main role is to dampen the activity of neurons in the brain and central nervous system, which results in a range of effects on the body and mind, including:

  • Reduced stress
  • Enhanced mood
  • Improved sleep quality
  • Increased feelings of relaxation

Commonly prescribed anxiety medications like Valium and Xanax work by increasing levels of GABA.

What is Ashwagandha?

ashwagandha plant

Ashwagandha (Withania Somnifera) is an ancient herb from India that’s been used for many thousand years.

And even today, Ashwagandha is used by many to promote feelings of calmness, strength, and vitality.

Ashwagandha is a member of the Nightshade family of plants, which includes popular vegetables like potatoes and aubergines.

Now let’s get stuck into the nitty gritty of these 2 supplements.


Benefits of GABA

GABA may improve sleep quality


According to research, insomnia sufferers have lower levels of GABA than the rest of us.

This could be due to the fact GABA helps the mind relax, so low GABA activity may cause you to overthink which disrupts sleep.

In one study, 100mg of GABA reduced the time it took for subjects to fall asleep by 5.3 minutes.

GABA may reduce stress and anxiety


Did you know that over 40 million US adults experience anxiety?

Shocking, right?

The good news is that lots of studies have shown GABA’s effectiveness at reducing stress and anxiety.

For example, a study investigated the effects of GABA on relaxation in 13 adults.

The subjects had increases in slow brain waves after an hour of taking GABA, which helped them relax and reduced their anxiety.

Another study looked at how GABA affects stress levels during a difficult task.

The results showed that GABA reduced the decrease in slow brain waves, suggesting that it may have lowered the subjects’ stress from the task.

GABA may help reduce high blood pressure

According to research, GABA may help reduce high blood pressure.

In one study, subjects with high(ish) blood pressure took Chlorella for 12 weeks.

(FYI, Chlorella is a type of algae that’s loaded with GABA.)

At the end of the 12 weeks, the subjects’ blood pressure was significantly reduced.

And so it’s not surprising to see many people take GABA to naturally lower their blood pressure.

Benefits of Ashwagandha

Ashwagandha may help boost muscle mass and strength


Despite being relatively unknown in the weightlifting community, Ashwagandha is an epic supplement for increasing muscle strength and size.

In a study of 57 people, some subjects took 600mg of daily Ashwagandha and the others took a placebo.

The results showed that the Ashwagandha users had bigger increases in size, strength, fat loss and testosterone levels.

Ashwagandha may help lower blood sugar levels


Research supports the use of Ashwagandha to lower your blood sugar levels.

A study looked at the blood sugar levels of 12 people after using Ashwagandha for a period of time.

After 30 days of Ashwagandha use, their blood sugar levels were lowered by amounts similar to that of blood sugar lowering medication.

Ashwagandha may help increase testosterone levels

A lot of people have lower than ideal testosterone levels nowadays.

This can be blamed on many things, such as:

  • Low fat diets
  • Poor sleep quality
  • High alcohol intake
  • High sugar consumption

But low testosterone levels are no laughing matter…

In fact, low T levels may be a common cause of depression in aging men. (Source)

If low T levels concern you, then perhaps you wanna give Ashwagandha a try as research shows it can boost T levels.

Ashwagandha may improve anxiety symptoms

Ashwagandha has shown some promising results at reducing anxiety in people.

For example, a 6-week study compared anxiety levels in people taking either Ashwagandha or a placebo.

At the end of the study, 88% of people who took Ashwagandha had less anxiety.

Another study had its subjects take either Ashwagandha or a placebo daily for 2 months.

The results showed that the Ashwagandha takers had a bigger reduction in scores on the “stress test” compared to the placebo takers.



GABA is generally sold as a powder or in capsules.

Typical prices for these are:

  • Powder: $20 for 1lb
  • Capsules: $22 for 100

Ashwagandha Cost

Ashwagandha is usually sold as a liquid extract or as tablets.

Here are some standard prices for these:

  • Tablets: $18 for 100
  • Liquid extract: $17 for 2 Oz

Side Effects

GABA Side Effects

GABA supplements are usually well tolerated by healthy adults, although the following side effects have been reported by some people:

  • Nausea
  • Constipation
  • Muscle weakness
  • Reduced appetite
  • Drowsiness and fatigue

Ashwagandha Side Effects

Like GABA, Ashwagandha supplements are usually safe to supplement with, but some mild side effects such as headaches and upset stomach have been reported in clinical studies.

Also, since Ashwagandha can lower your blood sugar levels, then please consult a doctor before taking it if you’re diabetic or are taking medication to lower your blood sugar levels.

The following people should NOT take Ashwagandha:

  • Pregnant women
  • People with stomach ulcers
  • Those with high/low blood pressure
  • People who’re allergic to Nightshade plants, i.e. Potatoes, Tomatoes, etc.
  • People with autoimmune conditions, i.e. Multiple Sclerosis, Rheumatoid Arthritis, etc.


My GABA Recommendation: Thorne Research PharmaGABA-100

Click to see on Amazon


This beauty is among the best GABA supplements on the market.

Perfect for those who prefer quality over quantity.

What I like about it

A quick glance at Thorne Research’s quality control process tells you how serious this brand is at making high-quality supplements.

In fact, some of the best supplements I’ve used have been from Thorne Research.

A great feature about their GABA is that it’s made from PharmaGABA.

This means it’s made naturally with bacteria.

(As opposed to synthetic GABA which is made in a lab from lots of chemical.)

Interestingly, PharmaGABA is believed to be more effective than synthetic GABA.

(Nature knows best, right?)

Its effectiveness is backed up by the numerous epic reviews, which shows that this is a trusted GABA supplement that’s used and loved by many other people.

Potential Drawbacks

The key downside is that PharmaGABA is a bit more expensive than synthetic GABA.

So those on a budget may opt for a cheaper (ahem, inferior) option.

Check price and read more reviews of Thorne Research PharmaGABA-100 on Amazon.

My Ashwagandha Recommendation: NaturaLife Labs Ashwagandha

Click to see on Amazon


High strength, high quality and fair priced.

NaturaLife Labs Ashwagandha gets the gold star.

What I like about it

1000s of excellent reviews show that many people are using and having great results with this supplement.

So there’s no reason why it won’t work for you.

Also, NaturaLife Labs have added black pepper to this supplement, which improves the absorption of the Ashwagandha, making this more effective than other Ashwagandha supps out there.

It’s the healthy option too, as it contains only natural ingredients and no nasty additives or preservatives.

Potential Drawbacks

With the recommended serving size being 3 capsules a day, the bottle will only last you a month, which isn’t ideal.

I mean, it’s certainly not a deal breaker by any means.

But it would be good if you could get bigger sized bottles.

Check price and read more reviews of NaturaLife Labs Ashwagandha on Amazon.

Can You Take GABA And Ashwagandha Together?

Yes, Ashwagandha and GABA can be taken together. Both are natural supplements that have different mechanisms of action and can complement each other’s effects. However, it’s always a good idea to consult with a healthcare professional before starting any new supplement regimen.

GABA vs Ashwagandha: The Verdict

Thanks for sticking to the end of this GABA vs Ashwagandha breakdown with me.

By now, you’ve hopefully decided which one’s ideal for you.

But if not, then here’s what I’d recommend:

You might prefer GABA if:

  • You want to improve your sleep
  • You want to lower your blood pressure
  • You want to perform better under times of stress

You might prefer Ashwagandha if:

  • You want to get stronger
  • You want to build muscle mass
  • You want to boost your T levels
  • You want to lower your blood sugar levels

That’s all for this article, but what about 5 HTP vs Ashwagandha? Or perhaps you’re interested in Ashwagandha vs L Theanine?

Hope this helped!


Does Ashwagandha act on GABA receptors?

While Ashwagandha does have an impact on neurotransmitters, including GABA, it does not directly act on GABA receptors. Instead, Ashwagandha has been found to have various effects on the GABA system, such as enhancing GABAergic activity and promoting a calming effect indirectly.

Does Ashwagandha have GABA?

Ashwagandha does not naturally contain GABA (gamma-aminobutyric acid). However, it has been shown to have an impact on GABA levels and activity in the brain, potentially influencing GABAergic neurotransmission indirectly.

Is GABA or Ashwagandha better for anxiety?

Both GABA and Ashwagandha have potential benefits for anxiety, but their mechanisms and effectiveness can vary for individuals. GABA may have a more direct calming effect, while Ashwagandha offers adaptogenic properties that can help manage stress and anxiety. Consult with a healthcare professional to determine the best option for you.

Is GABA or Ashwagandha better for sleep?

Both GABA and Ashwagandha have been studied for their potential sleep-promoting effects. GABA may help with relaxation and sleep quality, while Ashwagandha’s adaptogenic properties can support stress reduction, which can indirectly contribute to better sleep. The effectiveness may vary for individuals, so consult with a healthcare professional for personalized recommendations.

Does Ashwagandha increase GABA?

Ashwagandha has been found to have modulatory effects on GABA levels and activity in the brain. While it does not directly increase GABA levels, it may enhance GABAergic neurotransmission or influence GABA receptors indirectly, contributing to a calming effect.

What is the difference between GABA and Ashwagandha?

GABA (gamma-aminobutyric acid) is an amino acid that functions as a neurotransmitter, known for its calming and inhibitory effects in the brain. Ashwagandha, on the other hand, is an herbal adaptogen with various potential benefits, including stress reduction, mood support, and potential modulation of GABAergic activity.


Tuesday 4th of January 2022

What about taking them together?


Friday 11th of March 2022

Hey Rick, you should probably check this with a medical doctor to be sure.


Tuesday 29th of June 2021

Wow, it definitely helps me to choose some supplements during this stressful era. Thanks a lot.


Wednesday 12th of January 2022

This was very helpful and informative. I was looking for information about take GABA and Ashwagandha together. What can you tell me about that? Would you recommend?


Saturday 18th of July 2020

I appreciate your information. It was very helpful. I think I'm going to try GABA. Thank you so much.


Saturday 1st of May 2021

Gaba with synergistic blend is better than Gaba as a solitary ingredient


Tuesday 21st of July 2020

You're most welcome, Richard :)

I'm pleased you found the article helpful.